Sensory Neuropathy (SN)
Inheritance:
Autosomal recessive
Symptoms:
Clinical signs include ataxia, abnormal gait, muscle atrophy, knuckling of the paws and hyperextended limbs. Urinary incontinence and regurgitation may occur as the disease progresses.
Description:
SN is a progressive, severe neurological disease caused by degeneration of nerve cells. Affected dogs present between 2-7 months of age. Affected dogs lose feeling in all limbs and develop an inability to recognise the position of limbs in space. Hind limbs tend to be more severely affected than front limbs. Affected dogs will often chew on their lower limbs and feet as they lose feeling resulting in severe wounds.
Affected dogs are often euthanised within 18 months of diagnosis due to quality of life concerns. Mainly found in dogs of ISDS origin including carrier dogs imported into Australia.
The mutation was identified and the DNA test developed by the Animal Health Trust UK in 2015.
Autosomal recessive
Symptoms:
Clinical signs include ataxia, abnormal gait, muscle atrophy, knuckling of the paws and hyperextended limbs. Urinary incontinence and regurgitation may occur as the disease progresses.
Description:
SN is a progressive, severe neurological disease caused by degeneration of nerve cells. Affected dogs present between 2-7 months of age. Affected dogs lose feeling in all limbs and develop an inability to recognise the position of limbs in space. Hind limbs tend to be more severely affected than front limbs. Affected dogs will often chew on their lower limbs and feet as they lose feeling resulting in severe wounds.
Affected dogs are often euthanised within 18 months of diagnosis due to quality of life concerns. Mainly found in dogs of ISDS origin including carrier dogs imported into Australia.
The mutation was identified and the DNA test developed by the Animal Health Trust UK in 2015.
