Genetic Diseases

DNA Tests available for hereditary diseases affecting border collies are:
● Collie Eye Anomaly/ Choroidal Hypoplasia (CEA/CH)
● Trapped Neutrophil Syndrome (TNS)
● Neuronal Ceroid Lipofuscinosis 5 (NCL5)
● Raine Syndrome /Canine Dental Hypomineralisation (RS or DH)
● Imerslund-Grasbeck Syndrome (IGS) [aka Intestinal Cobalamin (Vit B12) Malabsortion (ICM)]
● Sensory Neuropathy (SN)
● Degenerative Myelopathy (DM)
● Multi Drug Resistance (MDR1)
● Goniodysgenesis predisposition (Goniodysgenesis/Glaucoma)
● Early Adult Onset Deafness (EAOD)
Physical Tests available for hereditary diseases or disorders affecting border collies:
● Hip and Elbow Dysplasia (HD and ED) – X-rays and Scoring by ANKC approved panel (CHEDS)
● Eye Diseases - CEA, Glaucoma, Progressive Retinal Atrophy (PRA), Primary Lens Luxation (PLL) - examinations/screening by Canine Opthalmologist (ANKC ACES)
Diseases for which no test is available:
● Discoid Lupus (Collie Nose)
● Epilepsy
● Border Collie Collapse (BCC)

Buyers should ask the breeder whether there is a history of these diseases in the parents. Parents affected by these conditions should not be bred from to reduce the risk of producing an affected puppy.

NBCC Genetic Disease Information Pages